20070913 BioKorea2007
From Jongbhak.com
Omics is a new paradigm of doing biological research. We can map most of biological research fields into various -omics such as genomics, proteomics, and interactomics. An example of using omics for protein structures and
their interaction is presented as protein structural interactomics.
Protein interactomics is the study of protein interactions in a holistic paradigm. It focuses on the action and interaction (and misinteraction) among proteins as information objects in cells. The fundamental unit of evolution is an interacting pair of structural objects, especially protein 3D structures. We mapped the protein structural family interaction that occurred in the last billions of years. It showed that the protein interactome has a distinct architecture that can explain the core of life in terms of interaction. Additionallly, structural interfaceomics is a study of all the protein interfaces from PDB. It maps interfaces and their geometrical and chemical properties.